6qzl

X-ray diffraction
1.98Å resolution

Structure of the H1 domain of human KCTD12

Released:
Source organism: Homo sapiens
Entry authors: Pinkas DM, Bufton JC, Fox AE, Newman JA, Kupinska K, Burgess-Brown NA, von Delft F, Arrowsmith CH, Edwards AM, Bountra C, Bullock AN, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
PDBe Complex ID:
PDB-CPX-188426 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BTB/POZ domain-containing protein KCTD12 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 126 amino acids
Theoretical weight: 14.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96CX2 (Residues: 202-325; Coverage: 38%)
Gene names: C13orf2, KCTD12, KIAA1778, PFET1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: C2221
Unit cell:
a: 88.32Å b: 91.36Å c: 152.26Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.204 0.248
Expression system: Escherichia coli