6r0e

X-ray diffraction
1.91Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-208754 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
HLA class II histocompatibility antigen, DR alpha chain Chain: AAA
Molecule details ›
Chain: AAA
Length: 183 amino acids
Theoretical weight: 21.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01903 (Residues: 26-207; Coverage: 80%)
Gene names: HLA-DRA, HLA-DRA1
Sequence domains:
HLA class II histocompatibility antigen, DRB1 beta chain Chain: BBB
Molecule details ›
Chain: BBB
Length: 191 amino acids
Theoretical weight: 22.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01911 (Residues: 30-219; Coverage: 80%)
Gene name: HLA-DRB1
Sequence domains:
Hemagglutinin HA1 chain Chain: CCC
Molecule details ›
Chain: CCC
Length: 13 amino acids
Theoretical weight: 1.51 KDa
Source organism: Influenza A virus
Expression system: Not provided
UniProt:
  • Canonical: P03435 (Residues: 323-335; Coverage: 2%)
Gene name: HA
F11-TCR Alpha Chain Chain: DDD
Molecule details ›
Chain: DDD
Length: 202 amino acids
Theoretical weight: 22.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
F11-TCR Beta Chain Chain: EEE
Molecule details ›
Chain: EEE
Length: 240 amino acids
Theoretical weight: 27.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21212
Unit cell:
a: 132.28Å b: 184.9Å c: 50.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.206 0.233
Expression systems:
  • Escherichia coli
  • Not provided