› 6r65

X-ray diffraction
3.5Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192646 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Anoctamin-10 Chains: A, B
Molecule details ›
Chains: A, B
Length: 667 amino acids
Theoretical weight: 77.28 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9NW15 (Residues: 1-660; Coverage: 100%)
Gene names: ANO10, TMEM16K
Sequence domains: Calcium-activated chloride channel

Ligands and Environments

1 bound ligand:
Ligand CA 6 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P212121
Unit cell:
a: 113.158Å b: 152.267Å c: 153.703Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.238 0.237 0.249
Expression system: Spodoptera frugiperda

Quick links

Citations

19 review citations

The diversity and breadth of cancer cell fatty acid metabolism.
Nagarajan et al. (2021)
18 more