Function and Biology Details
Reaction catalysed:
ATP-dependent breakage, passage and rejoining of double-stranded DNA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- DNA topoisomerase, type IIA, subunit B
- DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat
- DNA topoisomerase, type IIA, domain A
- TOPRIM domain
- DNA topoisomerase, type IIA, subunit B, C-terminal
- Histidine kinase/HSP90-like ATPase
- DNA gyrase, subunit B
- Histidine kinase/HSP90-like ATPase superfamily
13 more domains
Structure analysis Details
Assembly composition:
hetero octamer (preferred)
Assembly name:
GyrA-GyrB DNA Gyrase complex and DNA (preferred)
PDBe Complex ID:
PDB-CPX-120552 (preferred)
Entry contents:
2 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (4 distinct):
DNA gyrase subunit A
Molecule details ›
DNA gyrase subunit B
Molecule details ›
Chains: B, D
Length: 804 amino acids
Theoretical weight: 90.07 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 804 amino acids
Theoretical weight: 90.07 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P0AES6 (Residues: 1-804; Coverage: 100%)
Sequence domains:
