› 6rz4

X-ray diffraction
2.7Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142148 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cysteinyl leukotriene receptor 1; Soluble cytochrome b562 Chain: A
Molecule details ›
Chain: A
Length: 423 amino acids
Theoretical weight: 47.93 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9Y271 (Residues: 1-222, 223-311; Coverage: 92%)
  • Canonical: P0ABE7 (Residues: 22-127; Coverage: 98%)
Gene names: CYSLT1, CYSLTR1, cybC
Sequence domains:

Ligands and Environments

4 bound ligands:
Ligand KNT 1 x KNT
Ligand NA 1 x NA
Ligand OLC 9 x OLC
Ligand OLA 1 x OLA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: P21
Unit cell:
a: 58.63Å b: 45.35Å c: 86.43Å
α: 90° β: 91.47° γ: 90°
R-values:
R R work R free
0.229 0.228 0.254
Expression system: Spodoptera frugiperda

Quick links

Citations

4 review citations

Ligand binding at the protein-lipid interface: strategic considerations for drug design.
Payandeh et al. (2021)
3 more

12 mentions without citation

G protein-coupled receptors: structure- and function-based drug discovery.
Yang et al. (2021)
11 more