› 6rz5

X-ray diffraction
2.53Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142148 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cysteinyl leukotriene receptor 1; Soluble cytochrome b562 Chains: A, B
Molecule details ›
Chains: A, B
Length: 423 amino acids
Theoretical weight: 47.93 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9Y271 (Residues: 1-222, 223-311; Coverage: 92%)
  • Canonical: P0ABE7 (Residues: 22-127; Coverage: 98%)
Gene names: CYSLT1, CYSLTR1, cybC
Sequence domains:

Ligands and Environments

5 bound ligands:
Ligand ZLK 3 x ZLK
Ligand OLC 17 x OLC
Ligand OLA 19 x OLA
Ligand 1PE 1 x 1PE
Ligand NA 2 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLAC LCLS BEAMLINE CXI
Spacegroup: P1
Unit cell:
a: 41.59Å b: 68.58Å c: 87.39Å
α: 76.31° β: 76.68° γ: 81.21°
R-values:
R R work R free
0.191 0.189 0.223
Expression system: Spodoptera frugiperda

Quick links

Citations

4 review citations

Ligand binding at the protein-lipid interface: strategic considerations for drug design.
Payandeh et al. (2021)
3 more

8 mentions without citation

G protein-coupled receptors: structure- and function-based drug discovery.
Yang et al. (2021)
7 more