› 6s4l

X-ray diffraction
2.42Å resolution

Structure of human KCTD1

Released:
DOI: 10.2210/pdb6s4l/pdb
PDB entry 6s4l coloured by chain, front view.
PDB entry 6s4l coloured by chain, side view.
PDB entry 6s4l coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Pinkas DM, Bufton JC, Fox AE, Pike ACW, Newman JA, Krojer T, Shrestha L, Burgess-Brown NA, von Delft F, Arrowsmith C, Edwards A, Bountra C, Bullock AN

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180732 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BTB/POZ domain-containing protein KCTD1 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 232 amino acids
Theoretical weight: 26.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q719H9 (Residues: 28-257; Coverage: 90%)
Gene names: C18orf5, KCTD1
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand NA 2 x NA
Ligand IOD 2 x IOD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21
Unit cell:
a: 67.454Å b: 95.87Å c: 104.343Å
α: 90° β: 92.16° γ: 90°
R-values:
R R work R free
0.247 0.245 0.28
Expression system: Escherichia coli

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