› 6s5h

X-ray diffraction
2Å resolution

Structure of the human RAB38 in complex with GTP

Released:
DOI: 10.2210/pdb6s5h/pdb
PDB entry 6s5h coloured by chain, front view.
PDB entry 6s5h coloured by chain, side view.
PDB entry 6s5h coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Diaz-Saez L, Jung S, von Delft F, Arrowsmith CH, Edwards A, Bountra C, Huber K, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157612 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related protein Rab-38 Chain: A
Molecule details ›
Chain: A
Length: 208 amino acids
Theoretical weight: 23.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P57729 (Residues: 1-207; Coverage: 98%)
Gene name: RAB38
Sequence domains: Ras family

Ligands and Environments

4 bound ligands:
Ligand GTP 1 x GTP
Ligand EDO 9 x EDO
Ligand MG 1 x MG
Ligand BR 3 x BR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: C2221
Unit cell:
a: 35.804Å b: 144.174Å c: 77.523Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.163 0.209
Expression system: Escherichia coli

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