6s9j

X-ray diffraction
2.7Å resolution

Crystal structure of TfR1 mimicry in complex with GP1 from MACV

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-100293 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Pre-glycoprotein polyprotein GP complex Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 168 amino acids
Theoretical weight: 19.34 KDa
Source organism: Mammarenavirus machupoense
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q8AZ57 (Residues: 85-244; Coverage: 32%)
Gene name: GPC
Sequence domains: Arenavirus glycoprotein
Transferrin receptor protein 1 Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 178 amino acids
Theoretical weight: 19.65 KDa
Source organism: Neotoma albigula
Expression system: Trichoplusia ni
UniProt:
  • Canonical: A0A060BIS8 (Residues: 190-384; Coverage: 22%)
Gene name: TfR1
Sequence domains: PA domain

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: P4322
Unit cell:
a: 104.626Å b: 104.626Å c: 281.363Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.243 0.241 0.266
Expression system: Trichoplusia ni