Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- SKP1/BTB/POZ domain superfamily
- Pentatricopeptide repeat
- Tetratricopeptide-like helical domain superfamily
- Potassium channel tetramerisation-type BTB domain
- S-adenosyl-L-methionine-dependent methyltransferase superfamily
- Pseudouridine synthase I, TruA, C-terminal
- Pseudouridine synthase, catalytic domain superfamily
- Acyl carrier protein
35 more domains
Structure analysis Details
Assembly composition:
hetero 72-mer (preferred)
PDBe Complex ID:
PDB-CPX-167461 (preferred)
Entry contents:
61 distinct polypeptide molecules
1 distinct RNA molecule
1 distinct RNA molecule
Macromolecules (62 distinct):
uS5m
Chain: CE
Molecule details ›
Chain: CE
Length: 435 amino acids
Theoretical weight: 50.15 KDa
Source organism: Trypanosoma brucei brucei
Length: 435 amino acids
Theoretical weight: 50.15 KDa
Source organism: Trypanosoma brucei brucei
bS6m
Chain: CF
Molecule details ›
Chain: CF
Length: 160 amino acids
Theoretical weight: 18.86 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 160 amino acids
Theoretical weight: 18.86 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q38BW5 (Residues: 1-160; Coverage: 100%)
uS8m
Chain: CH
Molecule details ›
Chain: CH
Length: 282 amino acids
Theoretical weight: 32.77 KDa
Source organism: Trypanosoma brucei brucei
Length: 282 amino acids
Theoretical weight: 32.77 KDa
Source organism: Trypanosoma brucei brucei
uS11m
Chain: CK
Molecule details ›
Chain: CK
Length: 326 amino acids
Theoretical weight: 37.95 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 326 amino acids
Theoretical weight: 37.95 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q389T7 (Residues: 1-326; Coverage: 100%)
uS15m
Chain: CO
Molecule details ›
Chain: CO
Length: 429 amino acids
Theoretical weight: 50.4 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 429 amino acids
Theoretical weight: 50.4 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q4GZ99 (Residues: 1-429; Coverage: 100%)
bS16m
Chain: CP
Molecule details ›
Chain: CP
Length: 188 amino acids
Theoretical weight: 22.08 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 188 amino acids
Theoretical weight: 22.08 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q384N9 (Residues: 1-188; Coverage: 100%)
uS17m
Chain: CQ
Molecule details ›
Chain: CQ
Length: 336 amino acids
Theoretical weight: 39.01 KDa
Source organism: Trypanosoma brucei brucei
Length: 336 amino acids
Theoretical weight: 39.01 KDa
Source organism: Trypanosoma brucei brucei
bS18m
Chain: CR
Molecule details ›
Chain: CR
Length: 320 amino acids
Theoretical weight: 36.99 KDa
Source organism: Trypanosoma brucei brucei
Length: 320 amino acids
Theoretical weight: 36.99 KDa
Source organism: Trypanosoma brucei brucei
mS22
Chain: Ca
Molecule details ›
Chain: Ca
Length: 602 amino acids
Theoretical weight: 73.06 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 602 amino acids
Theoretical weight: 73.06 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q38DR3 (Residues: 1-602; Coverage: 100%)
mS23
Chain: Cb
Molecule details ›
Chain: Cb
Length: 311 amino acids
Theoretical weight: 35.36 KDa
Source organism: Trypanosoma brucei brucei
Length: 311 amino acids
Theoretical weight: 35.36 KDa
Source organism: Trypanosoma brucei brucei
mS26
Chain: Cd
Molecule details ›
Chain: Cd
Length: 440 amino acids
Theoretical weight: 51.14 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 440 amino acids
Theoretical weight: 51.14 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q38DK6 (Residues: 1-440; Coverage: 100%)
mS34
Chain: Cj
Molecule details ›
Chain: Cj
Length: 257 amino acids
Theoretical weight: 28.73 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 257 amino acids
Theoretical weight: 28.73 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q57UK0 (Residues: 1-257; Coverage: 100%)
mS38
Chain: Cn
Molecule details ›
Chain: Cn
Length: 250 amino acids
Theoretical weight: 28.24 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 250 amino acids
Theoretical weight: 28.24 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q57VQ9 (Residues: 1-250; Coverage: 100%)
Small ribosomal subunit protein mS41
Chain: Cp
Molecule details ›
Chain: Cp
Length: 187 amino acids
Theoretical weight: 22.42 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 187 amino acids
Theoretical weight: 22.42 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q389L3 (Residues: 1-187; Coverage: 100%)
mS51 (KRIPP1)
Chain: DD
Molecule details ›
Chain: DD
Length: 812 amino acids
Theoretical weight: 95.08 KDa
Source organism: Trypanosoma brucei brucei
Length: 812 amino acids
Theoretical weight: 95.08 KDa
Source organism: Trypanosoma brucei brucei
mS56
Chain: DI
Molecule details ›
Chain: DI
Length: 407 amino acids
Theoretical weight: 47.31 KDa
Source organism: Trypanosoma brucei brucei
Length: 407 amino acids
Theoretical weight: 47.31 KDa
Source organism: Trypanosoma brucei brucei
mS59
Chain: DL
Molecule details ›
Chain: DL
Length: 307 amino acids
Theoretical weight: 35.4 KDa
Source organism: Trypanosoma brucei brucei
Length: 307 amino acids
Theoretical weight: 35.4 KDa
Source organism: Trypanosoma brucei brucei
mS62 (KRIPP14)
Chain: DO
Molecule details ›
Chain: DO
Length: 282 amino acids
Theoretical weight: 32.07 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 282 amino acids
Theoretical weight: 32.07 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q383D1 (Residues: 1-282; Coverage: 100%)
mS63 (KRIPP16)
Chain: DP
Molecule details ›
Chain: DP
Length: 274 amino acids
Theoretical weight: 31.92 KDa
Source organism: Trypanosoma brucei brucei
Length: 274 amino acids
Theoretical weight: 31.92 KDa
Source organism: Trypanosoma brucei brucei
mS65
Chain: DR
Molecule details ›
Chain: DR
Length: 270 amino acids
Theoretical weight: 30.62 KDa
Source organism: Trypanosoma brucei brucei
Length: 270 amino acids
Theoretical weight: 30.62 KDa
Source organism: Trypanosoma brucei brucei
mS68
Chain: DU
Molecule details ›
Chain: DU
Length: 228 amino acids
Theoretical weight: 26.47 KDa
Source organism: Trypanosoma brucei brucei
Length: 228 amino acids
Theoretical weight: 26.47 KDa
Source organism: Trypanosoma brucei brucei
mS73
Chain: DZ
Molecule details ›
Chain: DZ
Length: 94 amino acids
Theoretical weight: 11.36 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 94 amino acids
Theoretical weight: 11.36 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q587C4 (Residues: 1-94; Coverage: 100%)
mt-SAF2 (KRIPP2)
Chain: F2
Molecule details ›
Chain: F2
Length: 1024 amino acids
Theoretical weight: 116.19 KDa
Source organism: Trypanosoma brucei brucei
Length: 1024 amino acids
Theoretical weight: 116.19 KDa
Source organism: Trypanosoma brucei brucei
Target SNARE
Chain: F3
Molecule details ›
Chain: F3
Length: 966 amino acids
Theoretical weight: 106.62 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 966 amino acids
Theoretical weight: 106.62 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q38E61 (Residues: 1-966; Coverage: 100%)
mt-SAF5
Chain: F5
Molecule details ›
Chain: F5
Length: 754 amino acids
Theoretical weight: 86.95 KDa
Source organism: Trypanosoma brucei brucei
Length: 754 amino acids
Theoretical weight: 86.95 KDa
Source organism: Trypanosoma brucei brucei
DUF4460 domain-containing protein
Chain: F6
Molecule details ›
Chain: F6
Length: 676 amino acids
Theoretical weight: 76.78 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Sequence domains: Domain of unknown function (DUF4460)
Length: 676 amino acids
Theoretical weight: 76.78 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q38FQ8 (Residues: 1-676; Coverage: 100%)
Sequence domains: Domain of unknown function (DUF4460)
Pentacotripeptide-repeat region of PRORP domain-containing protein
Chain: F7
Molecule details ›
Chain: F7
Length: 679 amino acids
Theoretical weight: 76.68 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 679 amino acids
Theoretical weight: 76.68 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q57UW6 (Residues: 1-679; Coverage: 100%)
mt-SAF8
Chain: F8
Molecule details ›
Chain: F8
Length: 726 amino acids
Theoretical weight: 76.73 KDa
Source organism: Trypanosoma brucei brucei
Length: 726 amino acids
Theoretical weight: 76.73 KDa
Source organism: Trypanosoma brucei brucei
mt-SAF9
Chain: F9
Molecule details ›
Chain: F9
Length: 608 amino acids
Theoretical weight: 69.78 KDa
Source organism: Trypanosoma brucei brucei
Length: 608 amino acids
Theoretical weight: 69.78 KDa
Source organism: Trypanosoma brucei brucei
mt-SAF10
Chain: FA
Molecule details ›
Chain: FA
Length: 642 amino acids
Theoretical weight: 69.31 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 642 amino acids
Theoretical weight: 69.31 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q386U1 (Residues: 1-642; Coverage: 100%)
mt-SAF11
Chains: FB, FC
Molecule details ›
Chains: FB, FC
Length: 579 amino acids
Theoretical weight: 64.92 KDa
Source organism: Trypanosoma brucei brucei
Length: 579 amino acids
Theoretical weight: 64.92 KDa
Source organism: Trypanosoma brucei brucei
mt-SAF13
Chain: FE
Molecule details ›
Chain: FE
Length: 553 amino acids
Theoretical weight: 63.69 KDa
Source organism: Trypanosoma brucei brucei
Length: 553 amino acids
Theoretical weight: 63.69 KDa
Source organism: Trypanosoma brucei brucei
mt-SAF18
Chain: FJ
Molecule details ›
Chain: FJ
Length: 362 amino acids
Theoretical weight: 42.51 KDa
Source organism: Trypanosoma brucei brucei
Length: 362 amino acids
Theoretical weight: 42.51 KDa
Source organism: Trypanosoma brucei brucei
mt-SAF21
Chains: FM, FN
Molecule details ›
Chains: FM, FN
Length: 370 amino acids
Theoretical weight: 39.61 KDa
Source organism: Trypanosoma brucei brucei
Length: 370 amino acids
Theoretical weight: 39.61 KDa
Source organism: Trypanosoma brucei brucei
mt-SAF22 (KRIPP17)
Chain: FO
Molecule details ›
Chain: FO
Length: 334 amino acids
Theoretical weight: 39.13 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 334 amino acids
Theoretical weight: 39.13 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q389F9 (Residues: 1-334; Coverage: 100%)
mt-SAF23
Chain: FP
Molecule details ›
Chain: FP
Length: 349 amino acids
Theoretical weight: 38.24 KDa
Source organism: Trypanosoma brucei brucei
Length: 349 amino acids
Theoretical weight: 38.24 KDa
Source organism: Trypanosoma brucei brucei
Potassium channel tetramerisation-type BTB domain-containing protein
Chains: FQ, FR, FS, FT, FU
Molecule details ›
Chains: FQ, FR, FS, FT, FU
Length: 307 amino acids
Theoretical weight: 34.65 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Sequence domains: BTB/POZ domain
Length: 307 amino acids
Theoretical weight: 34.65 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q387P8 (Residues: 1-307; Coverage: 100%)
Sequence domains: BTB/POZ domain
Phosphotyrosine protein phosphatase I domain-containing protein
Chain: FW
Molecule details ›
Chain: FW
Length: 263 amino acids
Theoretical weight: 30.54 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Sequence domains: Low molecular weight phosphotyrosine protein phosphatase
Length: 263 amino acids
Theoretical weight: 30.54 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q38FI3 (Residues: 1-263; Coverage: 100%)
Sequence domains: Low molecular weight phosphotyrosine protein phosphatase
Pentacotripeptide-repeat region of PRORP domain-containing protein
Chain: FX
Molecule details ›
Chain: FX
Length: 239 amino acids
Theoretical weight: 26.94 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Sequence domains: Pentatricopeptide repeat domain
Length: 239 amino acids
Theoretical weight: 26.94 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q57YK5 (Residues: 1-239; Coverage: 100%)
Sequence domains: Pentatricopeptide repeat domain
mt-SAF28
Chain: FY
Molecule details ›
Chain: FY
Length: 188 amino acids
Theoretical weight: 21.47 KDa
Source organism: Trypanosoma brucei brucei
Length: 188 amino acids
Theoretical weight: 21.47 KDa
Source organism: Trypanosoma brucei brucei
mt-SAF29
Chain: FZ
Molecule details ›
Chain: FZ
Length: 178 amino acids
Theoretical weight: 20.05 KDa
Source organism: Trypanosoma brucei brucei
Length: 178 amino acids
Theoretical weight: 20.05 KDa
Source organism: Trypanosoma brucei brucei
Glutaredoxin domain-containing protein
Chain: Fa
Molecule details ›
Chain: Fa
Length: 171 amino acids
Theoretical weight: 19.66 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 171 amino acids
Theoretical weight: 19.66 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q57VU7 (Residues: 1-171; Coverage: 100%)
Succinate dehydrogenase assembly factor 3, mitochondrial
Chain: Fb
Molecule details ›
Chain: Fb
Length: 151 amino acids
Theoretical weight: 17.67 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Length: 151 amino acids
Theoretical weight: 17.67 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q581U4 (Residues: 1-151; Coverage: 100%)
Acyl carrier protein
Chain: Fc
Molecule details ›
Chain: Fc
Length: 148 amino acids
Theoretical weight: 16.55 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Sequence domains: Phosphopantetheine attachment site
Length: 148 amino acids
Theoretical weight: 16.55 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q57WW9 (Residues: 1-148; Coverage: 100%)
Sequence domains: Phosphopantetheine attachment site
Probable Zinc-ribbon domain-containing protein
Chain: Fd
Molecule details ›
Chain: Fd
Length: 143 amino acids
Theoretical weight: 16.29 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Sequence domains: Probable Zinc-ribbon domain
Length: 143 amino acids
Theoretical weight: 16.29 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q581T4 (Residues: 1-143; Coverage: 100%)
Sequence domains: Probable Zinc-ribbon domain
UNK-A
Chain: UA
Molecule details ›
Chain: UA
Length: 21 amino acids
Theoretical weight: 1.81 KDa
Source organism: Trypanosoma brucei brucei
Length: 21 amino acids
Theoretical weight: 1.81 KDa
Source organism: Trypanosoma brucei brucei
UNK-B
Chain: UB
Molecule details ›
Chain: UB
Length: 27 amino acids
Theoretical weight: 2.32 KDa
Source organism: Trypanosoma brucei brucei
Length: 27 amino acids
Theoretical weight: 2.32 KDa
Source organism: Trypanosoma brucei brucei
UNK-C
Chain: UC
Molecule details ›
Chain: UC
Length: 10 amino acids
Theoretical weight: 869 Da
Source organism: Trypanosoma brucei brucei
Length: 10 amino acids
Theoretical weight: 869 Da
Source organism: Trypanosoma brucei brucei
UNK-D, UNK-M, UNK-Q
Chains: UD, UM, UQ
Molecule details ›
Chains: UD, UM, UQ
Length: 9 amino acids
Theoretical weight: 784 Da
Source organism: Trypanosoma brucei brucei
Length: 9 amino acids
Theoretical weight: 784 Da
Source organism: Trypanosoma brucei brucei
UNK-E, UNK-P
Chains: UE, UP
Molecule details ›
Chains: UE, UP
Length: 45 amino acids
Theoretical weight: 3.85 KDa
Source organism: Trypanosoma brucei brucei
Length: 45 amino acids
Theoretical weight: 3.85 KDa
Source organism: Trypanosoma brucei brucei
UNK-F
Chain: UF
Molecule details ›
Chain: UF
Length: 11 amino acids
Theoretical weight: 954 Da
Source organism: Trypanosoma brucei brucei
Length: 11 amino acids
Theoretical weight: 954 Da
Source organism: Trypanosoma brucei brucei
UNK-G
Chain: UG
Molecule details ›
Chain: UG
Length: 17 amino acids
Theoretical weight: 1.46 KDa
Source organism: Trypanosoma brucei brucei
Length: 17 amino acids
Theoretical weight: 1.46 KDa
Source organism: Trypanosoma brucei brucei
UNK-H
Chain: UH
Molecule details ›
Chain: UH
Length: 5 amino acids
Theoretical weight: 444 Da
Source organism: Trypanosoma brucei brucei
Length: 5 amino acids
Theoretical weight: 444 Da
Source organism: Trypanosoma brucei brucei
UNK-I, UNK-M
Chains: UI, UN
Molecule details ›
Chains: UI, UN
Length: 8 amino acids
Theoretical weight: 699 Da
Source organism: Trypanosoma brucei brucei
Length: 8 amino acids
Theoretical weight: 699 Da
Source organism: Trypanosoma brucei brucei
UNK-J
Chain: UJ
Molecule details ›
Chain: UJ
Length: 16 amino acids
Theoretical weight: 1.38 KDa
Source organism: Trypanosoma brucei brucei
Length: 16 amino acids
Theoretical weight: 1.38 KDa
Source organism: Trypanosoma brucei brucei
UNK-L
Chain: UL
Molecule details ›
Chain: UL
Length: 22 amino acids
Theoretical weight: 1.89 KDa
Source organism: Trypanosoma brucei brucei
Length: 22 amino acids
Theoretical weight: 1.89 KDa
Source organism: Trypanosoma brucei brucei
UNK-O
Chain: UO
Molecule details ›
Chain: UO
Length: 30 amino acids
Theoretical weight: 2.57 KDa
Source organism: Trypanosoma brucei brucei
Length: 30 amino acids
Theoretical weight: 2.57 KDa
Source organism: Trypanosoma brucei brucei
UNK-U
Chain: UU
Molecule details ›
Chain: UU
Length: 24 amino acids
Theoretical weight: 2.06 KDa
Source organism: Trypanosoma brucei brucei
Length: 24 amino acids
Theoretical weight: 2.06 KDa
Source organism: Trypanosoma brucei brucei
UNK-I
Chain: UY
Molecule details ›
Chain: UY
Length: 468 amino acids
Theoretical weight: 39.85 KDa
Source organism: Trypanosoma brucei brucei
Length: 468 amino acids
Theoretical weight: 39.85 KDa
Source organism: Trypanosoma brucei brucei
Methyltransferase
Chain: F1
Molecule details ›
Chain: F1
Length: 1041 amino acids
Theoretical weight: 119.8 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Sequence domains: Mitochondrial small ribosomal subunit Rsm22
Length: 1041 amino acids
Theoretical weight: 119.8 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q385R2 (Residues: 1-1041; Coverage: 100%)
Sequence domains: Mitochondrial small ribosomal subunit Rsm22
S-adenosyl-methyltransferase mraW-like protein, putative
Chain: FF
Molecule details ›
Chain: FF
Length: 474 amino acids
Theoretical weight: 53.32 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
Sequence domains: MraW methylase family
Length: 474 amino acids
Theoretical weight: 53.32 KDa
Source organism: Trypanosoma brucei brucei
UniProt:
- Canonical: Q57W60 (Residues: 1-474; Coverage: 100%)
Sequence domains: MraW methylase family
9S rRNA
Chain: CA
Molecule details ›
Chain: CA
Length: 474 nucleotides
Theoretical weight: 151.51 KDa
Sequence domains: Trypanosomatid mitochondrial small subunit ribosomal RNA
Length: 474 nucleotides
Theoretical weight: 151.51 KDa
Sequence domains: Trypanosomatid mitochondrial small subunit ribosomal RNA