› 6sgy

Electron Microscopy
4.6Å resolution

Structure of EccB3 dimer from the ESX-3 core complex

Released:
DOI: 10.2210/pdb6sgy/pdb
PDB entry 6sgy coloured by chain, front view.
PDB entry 6sgy coloured by chain, side view.
PDB entry 6sgy coloured by chain, top view.
Source organism: Mycolicibacterium smegmatis MC2 155
Primary publication:
Architecture of the mycobacterial type VII secretion system.
Famelis N, Rivera-Calzada A, Degliesposti G, Wingender M, Mietrach N, Skehel JM, Fernandez-Leiro R, Böttcher B, Schlosser A, Llorca O, Geibel S
Nature 576 321-325 (2019)
PMID: 31597161
Related structures: EMD-10188

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-106243 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ESX-3 secretion system ATPase EccB3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 419 amino acids
Theoretical weight: 42.75 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
Expression system: Mycolicibacterium smegmatis MC2 155
UniProt:
  • Canonical: A0QQ39 (Residues: 100-518; Coverage: 81%)
Gene names: MSMEG_0616, MSMEI_0600, eccB3
Sequence domains: Type VII secretion system ESX-1, transport TM domain B

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.6Å
Relevant EMDB volumes: EMD-10188
Expression system: Mycolicibacterium smegmatis MC2 155

Quick links

Citations

9 review citations

Transporters Involved in the Biogenesis and Functionalization of the Mycobacterial Cell Envelope.
Jackson et al. (2021)
8 more

3 mentions without citation

Recent Insights into the Structure and Function of Mycobacterial Membrane Proteins Facilitated by Cryo-EM.
Bendre et al. (2021)
2 more