Function and Biology Details
Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
- G-patch domain
- Helicase, C-terminal domain-like
- P-loop containing nucleoside triphosphate hydrolase
- Helicase-associated domain
- Helicase superfamily 1/2, ATP-binding domain
- G patch domain and ankyrin repeat-containing protein 1
- DEAD-box helicase, OB fold
- DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
2 more domains
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127356 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
ATP-dependent RNA helicase DHX15
Molecule details ›
Chain: A
Length: 689 amino acids
Theoretical weight: 79.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 689 amino acids
Theoretical weight: 79.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
O43143 (Residues: 113-795; Coverage: 86%)
Sequence domains:
NF-kappa-B-repressing factor
Molecule details ›
Chain: B
Length: 67 amino acids
Theoretical weight: 7.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: G-patch domain
Length: 67 amino acids
Theoretical weight: 7.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: O15226 (Residues: 541-603; Coverage: 9%)
Sequence domains: G-patch domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SLS BEAMLINE X06SA
Spacegroup:
C2221
Expression system: Escherichia coli BL21(DE3)
