› 6smv

X-ray diffraction
2.14Å resolution

Structure of HPV49 E6 protein in complex with MAML1 LxxLL motif

Released:
DOI: 10.2210/pdb6smv/pdb
PDB entry 6smv coloured by chain, front view.
PDB entry 6smv coloured by chain, side view.
PDB entry 6smv coloured by chain, top view.
Source organisms:
Entry authors: Suarez IP, Cousido-Siah A, Bonhoure A, Kostmann C, Mitschler A, Podjarny A, Trave G

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142534 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Maltose/maltodextrin-binding periplasmic protein; Mastermind-like protein 1; Protein E6 Chain: A
Molecule details ›
Chain: A
Length: 538 amino acids
Theoretical weight: 59.26 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0AEX9 (Residues: 26-392; Coverage: 99%)
  • Canonical: P36813 (Residues: 1-138; Coverage: 100%)
  • Canonical: Q92585 (Residues: 1003-1016; Coverage: 1%)
Gene names: E6, JW3994, KIAA0200, MAML1, b4034, malE
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
Carbohydrate polymer
2 bound ligands:
Ligand ZN 2 x ZN
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P21
Unit cell:
a: 73.906Å b: 44.539Å c: 94.237Å
α: 90° β: 99.705° γ: 90°
R-values:
R R work R free
0.22 0.218 0.255
Expression system: Escherichia coli BL21(DE3)

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