› 6sqi

X-ray diffraction
1.6Å resolution

Crystal structure of mouse PRMT6 with C-terminal TEV cleavage site

Released:
DOI: 10.2210/pdb6sqi/pdb
Model geometry
Fit model/data
PDB entry 6sqi coloured by chain, front view.
PDB entry 6sqi coloured by chain, side view.
PDB entry 6sqi coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Bonnefond L, Cavarelli J

Function and Biology Details

Reaction catalysed: 
(1a) S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-N(omega)-methyl-L-arginine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180090 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein arginine N-methyltransferase 6 Chain: A
Molecule details ›
Chain: A
Length: 386 amino acids
Theoretical weight: 42.82 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6NZB1 (Residues: 1-378; Coverage: 100%)
Gene names: Hrmt1l6, Prmt6
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: RIGAKU FR-X
Spacegroup: I41
Unit cell:
a: 79.644Å b: 79.644Å c: 117.738Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.147 0.144 0.167
Expression system: Escherichia coli BL21(DE3)

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