› 6sr8

X-ray diffraction
1.94Å resolution

Crystal structure of glutathione transferase Omega 2C from Trametes versicolor

Released:
DOI: 10.2210/pdb6sr8/pdb
PDB entry 6sr8 coloured by chain, front view.
PDB entry 6sr8 coloured by chain, side view.
PDB entry 6sr8 coloured by chain, top view.
Source organism: Trametes versicolor FP-101664 SS1
Primary publication:
Diversity of Omega Glutathione Transferases in mushroom-forming fungi revealed by phylogenetic, transcriptomic, biochemical and structural approaches.
Perrot T, Schwartz M, Deroy A, Girardet JM, Kohler A, Morel-Rouhier M, Favier F, Gelhaye E, Didierjean C
Fungal Genet Biol 148 103506 (2021)
PMID: 33450403

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195801 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GST N-terminal domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 245 amino acids
Theoretical weight: 27.43 KDa
Source organism: Trametes versicolor FP-101664 SS1
Expression system: Escherichia coli
UniProt:
  • Canonical: R7S7J5 (Residues: 1-239; Coverage: 100%)
Gene name: TRAVEDRAFT_67635
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand GSH 2 x GSH
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: C2
Unit cell:
a: 68.49Å b: 141.96Å c: 65.37Å
α: 90° β: 116.21° γ: 90°
R-values:
R R work R free
0.198 0.196 0.253
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Effects of Glucosinolate-Derived Isothiocyanates on Fungi: A Comprehensive Review on Direct Effects, Mechanisms, Structure-Activity Relationship Data and Possible Agricultural Applications.
Plaszkó et al. (2021)
1 more

1 mention without citation

Robust AMBER Force Field Parameters for Glutathionylated Cysteines.
Elftmaoui et al. (2023)