Function and Biology Details
Reaction catalysed:
Selective cleavage of Arg-|-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa.
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133247 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Complement component 1 Q subcomponent-binding protein, mitochondrial
Molecule details ›
Chains: A, B, C
Length: 209 amino acids
Theoretical weight: 23.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Mitochondrial glycoprotein
Length: 209 amino acids
Theoretical weight: 23.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q07021 (Residues: 74-282; Coverage: 74%)
Sequence domains: Mitochondrial glycoprotein
Coagulation factor XIIa heavy chain
Molecule details ›
Chain: D
Length: 71 amino acids
Theoretical weight: 8.46 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
Sequence domains: Fibronectin type II domain
Length: 71 amino acids
Theoretical weight: 8.46 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
- Canonical: P00748 (Residues: 20-90; Coverage: 12%)
Sequence domains: Fibronectin type II domain
