› 6t1s

X-ray diffraction
1.65Å resolution

PPAR mutant

Released:
DOI: 10.2210/pdb6t1s/pdb
PDB entry 6t1s coloured by chain, front view.
PDB entry 6t1s coloured by chain, side view.
PDB entry 6t1s coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Rochel N

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153379 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxisome proliferator-activated receptor gamma Chain: A
Molecule details ›
Chain: A
Length: 279 amino acids
Theoretical weight: 31.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P37231 (Residues: 231-505; Coverage: 55%)
Gene names: NR1C3, PPARG
Sequence domains: Ligand-binding domain of nuclear hormone receptor

Ligands and Environments

2 bound ligands:
Ligand EDK 1 x EDK
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P41212
Unit cell:
a: 60.66Å b: 60.66Å c: 169.52Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.171 0.204
Expression system: Escherichia coli BL21(DE3)

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