Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero 240-mer (preferred)
Assembly name:
VP1 (preferred)
PDBe Complex ID:
PDB-CPX-173707 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
VP1
Molecule details ›
Chain: A
Length: 275 amino acids
Theoretical weight: 30.25 KDa
Source organism: Enterovirus F
UniProt:
Length: 275 amino acids
Theoretical weight: 30.25 KDa
Source organism: Enterovirus F
UniProt:
- Canonical:
Q2LKZ0 (Residues: 559-833; Coverage: 13%)
VP2
Molecule details ›
Chain: B
Length: 244 amino acids
Theoretical weight: 26.76 KDa
Source organism: Enterovirus F
UniProt:
Length: 244 amino acids
Theoretical weight: 26.76 KDa
Source organism: Enterovirus F
UniProt:
- Canonical: Q2LKZ0 (Residues: 72-315; Coverage: 11%)
VP3
Molecule details ›
Chain: C
Length: 243 amino acids
Theoretical weight: 27.15 KDa
Source organism: Enterovirus F
UniProt:
Length: 243 amino acids
Theoretical weight: 27.15 KDa
Source organism: Enterovirus F
UniProt:
- Canonical: Q2LKZ0 (Residues: 316-558; Coverage: 11%)
VP4
Molecule details ›
Chain: D
Length: 71 amino acids
Theoretical weight: 7.71 KDa
Source organism: Enterovirus F
UniProt:
Length: 71 amino acids
Theoretical weight: 7.71 KDa
Source organism: Enterovirus F
UniProt:
- Canonical: Q2LKZ0 (Residues: 1-71; Coverage: 3%)
