› 6tt8

Solution NMR

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123186 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metallo-beta-lactamase type 2 Chain: A
Molecule details ›
Chain: A
Length: 227 amino acids
Theoretical weight: 23.97 KDa
Source organism: Klebsiella pneumoniae
Expression system: Escherichia coli
UniProt:
  • Canonical: E9NWK5 (Residues: 43-269; Coverage: 84%)
Gene names: D647_p47098, EC13450_007, G4V31_29050, MYA94_26190, NCTC13443_00040, NDM-1, SAMEA3499901_05193, TR3_031, TR4_031, bla NDM-1, blaNDM-1, blaNDM1, p2146_00143, pCRE380_21, pN11x00042NDM_090, pNDM-SX04_5, pNDM10469_138
Sequence domains: Metallo-beta-lactamase superfamily

Ligands and Environments

2 bound ligands:
Ligand ZN 2 x ZN
Ligand MRI 1 x MRI
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 39%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

9 citation in other articles

Binding of 2-(Triazolylthio)acetamides to Metallo-β-lactamase CcrA Determined with NMR.
Andersson et al. (2020)
8 more

1 mention without citation

NMR Characterization of the Influence of Zinc(II) Ions on the Structural and Dynamic Behavior of the New Delhi Metallo-β-Lactamase-1 and on the Binding with Flavonols as Inhibitors.
Rivière et al. (2020)