› 6tul

X-ray diffraction
2.25Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-214211 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fab C0021177 heavy chain (IgG1) Chain: HHH
Molecule details ›
Chain: HHH
Length: 233 amino acids
Theoretical weight: 24.61 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Fab C0021177 light chain (IgG1) Chain: LLL
Molecule details ›
Chain: LLL
Length: 220 amino acids
Theoretical weight: 23.1 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus

Ligands and Environments

4 bound ligands:
Ligand PG4 2 x PG4
Ligand P6G 1 x P6G
Ligand MLT 2 x MLT
Ligand PGE 2 x PGE
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P212121
Unit cell:
a: 53.537Å b: 69.244Å c: 106.517Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.252 0.248 0.318
Expression system: Cricetulus griseus

Quick links

Citations

1 review citation

Targeting amino acid-metabolizing enzymes for cancer immunotherapy.
Grobben Y. (2024)
2 other articles

2 mentions without citation

Widespread impact of immunoglobulin V-gene allelic polymorphisms on antibody reactivity.
Yuan et al. (2023)
1 more