› 6u3g

Electron Microscopy
53Å resolution

Best fitting antiparallel model for Volume 2 of truncated dimeric Cytohesin-3 (Grp1; amino acids 14-399)

Released:
DOI: 10.2210/pdb6u3g/pdb
PDB entry 6u3g coloured by chain, front view.
PDB entry 6u3g coloured by chain, side view.
PDB entry 6u3g coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes.
Das S, Malaby AW, Nawrotek A, Zhang W, Zeghouf M, Maslen S, Skehel M, Chakravarthy S, Irving TC, Bilsel O, Cherfils J, Lambright DG
Structure 27 1782-1797.e7 (2019)
PMID: 31601460
Related structures: EMD-20629

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129090 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytohesin-3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 397 amino acids
Theoretical weight: 46.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O43739 (Residues: 13-400; Coverage: 97%)
Gene names: ARNO3, CYTH3, GRP1, PSCD3
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand 4IP 2 x 4IP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 53Å
Relevant EMDB volumes: EMD-20629
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Physiological and Pathological Roles of the Cytohesin Family in Neurons.
Ito et al. (2022)
5 other articles

1 mention without citation

Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes.
Das et al. (2019)