› 6u5n

Electron Microscopy
3.2Å resolution

Calcium-bound MthK gating ring state 2

Released:
DOI: 10.2210/pdb6u5n/pdb
PDB entry 6u5n coloured by chain, front view.
PDB entry 6u5n coloured by chain, side view.
PDB entry 6u5n coloured by chain, top view.
Source organism: Methanothermobacter thermautotrophicus
Primary publication:
Ball-and-chain inactivation in a calcium-gated potassium channel.
Fan C, Sukomon N, Flood E, Rheinberger J, Allen TW, Nimigean CM
Nature 580 288-293 (2020)
PMID: 32269335
Related structures: EMD-20650

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127900 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-gated potassium channel MthK Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 336 amino acids
Theoretical weight: 37.36 KDa
Source organism: Methanothermobacter thermautotrophicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O27564 (Residues: 1-336; Coverage: 100%)
Gene names: MTH_1520, mthK
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand CA 24 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.2Å
Relevant EMDB volumes: EMD-20650
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Molecular Mechanisms for Bacterial Potassium Homeostasis.
Stautz et al. (2021)
3 more

1 mention without citation

Ball-and-chain inactivation in a calcium-gated potassium channel.
Fan et al. (2020)