› 6u6d

Electron Microscopy
3.6Å resolution

MthK closed state with EDTA

Released:
DOI: 10.2210/pdb6u6d/pdb
PDB entry 6u6d coloured by chain, front view.
PDB entry 6u6d coloured by chain, side view.
PDB entry 6u6d coloured by chain, top view.
Source organism: Methanothermobacter thermautotrophicus
Primary publication:
Ball-and-chain inactivation in a calcium-gated potassium channel.
Fan C, Sukomon N, Flood E, Rheinberger J, Allen TW, Nimigean CM
Nature 580 288-293 (2020)
PMID: 32269335
Related structures: EMD-20663

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127900 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-gated potassium channel MthK Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 336 amino acids
Theoretical weight: 37.36 KDa
Source organism: Methanothermobacter thermautotrophicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O27564 (Residues: 1-336; Coverage: 100%)
Gene names: MTH_1520, mthK
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand K 2 x K
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.6Å
Relevant EMDB volumes: EMD-20663
Expression system: Escherichia coli

Quick links

Citations

3 review citations

P-Loop Channels: Experimental Structures, and Physics-Based and Neural Networks-Based Models.
Tikhonov et al. (2022)
2 more

6 mentions without citation

Molecular Mechanisms for Bacterial Potassium Homeostasis.
Stautz et al. (2021)
5 more