› 6u95

Electron Microscopy
2.56Å resolution

Adeno-associated virus strain AAVhu.37 capsid icosahedral structure

Released:
DOI: 10.2210/pdb6u95/pdb
PDB entry 6u95 coloured by chain, front view.
PDB entry 6u95 coloured by chain, side view.
PDB entry 6u95 coloured by chain, top view.
Source organism: Adeno-associated virus
Primary publication:
Structure of the AAVhu.37 capsid by cryoelectron microscopy.
Kaelber JT, Yost SA, Webber KA, Firlar E, Liu Y, Danos O, Mercer AC
Acta Crystallogr F Struct Biol Commun 76 58-64 (2020)
PMID: 32039886
Related structures: EMD-20693

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 60-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179809 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein VP1 Chain: A
Molecule details ›
Chain: A
Length: 737 amino acids
Theoretical weight: 81.53 KDa
Source organism: Adeno-associated virus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q6JC19 (Residues: 2-738; Coverage: 100%)
Gene name: cap
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.56Å
Relevant EMDB volumes: EMD-20693
Expression system: Homo sapiens

Quick links

Citations

8 citation in other articles

Adeno-associated virus capsid assembly is divergent and stochastic.
Wörner et al. (2021)
7 more

3 mentions without citation

Cryo-electron Microscopy of Adeno-associated Virus.
Stagg et al. (2022)
2 more