› 6uda

Electron Microscopy
4.2Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-207999 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (5 distinct):
Envelope glycoprotein gp160 Chains: A, E, I
Molecule details ›
Chains: A, E, I
Length: 487 amino acids
Theoretical weight: 54.55 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: M4M0W3 (Residues: 31-489; Coverage: 54%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120
CH235 UCA heavy chain Fab Chains: C, G, K
Molecule details ›
Chains: C, G, K
Length: 249 amino acids
Theoretical weight: 26.64 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Transmembrane protein gp41 Chains: F, J, Z
CH235 UCA light chain Fab Chains: D, H, L

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
1 bound ligand:
Ligand NAG 6 x NAG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 4.2Å
Relevant EMDB volumes: EMD-20735
Expression system: Homo sapiens

Quick links

Citations

12 review citations

Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies.
Haynes et al. (2023)
11 more

10 mentions without citation

Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.
Wang et al. (2022)
9 more