› 6uhi

X-ray diffraction
2.88Å resolution

Closed-form Crystal Structure of Chimera Bt-hRyR_12 from Bacteroides thetaiotaomicron /human

Released:
DOI: 10.2210/pdb6uhi/pdb
PDB entry 6uhi coloured by chain, front view.
PDB entry 6uhi coloured by chain, side view.
PDB entry 6uhi coloured by chain, top view.
Source organisms:
Entry authors: Wu R, Jedrzejczak R, KIm Y, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149435 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ryanodine receptor 1; Ryanodine receptor Ryr domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 214 amino acids
Theoretical weight: 25.83 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P21817 (Residues: 849-962; Coverage: 2%)
  • Canonical: Q8A5J2 (Residues: 1-100; Coverage: 100%)
Gene names: BT_2247, RYDR, RYR1
Sequence domains: RyR domain

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
1 modified residue:
Ligand MSE 9 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P32
Unit cell:
a: 51.913Å b: 51.913Å c: 85.174Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.235 0.227 0.273
Expression system: Escherichia coli BL21(DE3)

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