Function and Biology Details
Reaction catalysed:
(1a) isocitrate + NADP(+) = 2-oxalosuccinate + NADPH
Biochemical function:
- not assigned
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-231691 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
HLA class I histocompatibility antigen, B alpha chain
Molecule details ›
Chain: A
Length: 298 amino acids
Theoretical weight: 34.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 298 amino acids
Theoretical weight: 34.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P01889 (Residues: 25-304; Coverage: 83%)
Sequence domains:
Beta-2-microglobulin
Molecule details ›
Chain: B
Length: 119 amino acids
Theoretical weight: 13.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Immunoglobulin C1-set domain
Length: 119 amino acids
Theoretical weight: 13.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P61769 (Residues: 1-119; Coverage: 100%)
Sequence domains: Immunoglobulin C1-set domain
Isocitrate dehydrogenase [NADP], mitochondrial
Molecule details ›
Chain: C
Length: 10 amino acids
Theoretical weight: 1.06 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 10 amino acids
Theoretical weight: 1.06 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P48735 (Residues: 134-143; Coverage: 2%)
