Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- WD40 repeat
- Guanine nucleotide binding protein (G-protein), alpha subunit
- GPCR, family 2, calcitonin receptor family
- GPCR, family 2, secretin-like
- GPCR, family 2, calcitonin gene-related peptide, type 1 receptor
- G-protein alpha subunit, group S
- G-protein gamma-like domain
- G-protein, gamma subunit
21 more domains
Structure analysis Details
Assembly composition:
hetero heptamer (preferred)
Assembly name:
Adrenomedullin receptor AM2 complex (preferred)
PDBe Complex ID:
PDB-CPX-208120 (preferred)
Entry contents:
7 distinct polypeptide molecules
Macromolecules (7 distinct):
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Molecule details ›
Chain: A
Length: 394 amino acids
Theoretical weight: 45.7 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: G-protein alpha subunit
Length: 394 amino acids
Theoretical weight: 45.7 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
P63092 (Residues: 1-394; Coverage: 100%)
Sequence domains: G-protein alpha subunit
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Molecule details ›
Chain: B
Length: 350 amino acids
Theoretical weight: 38.53 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: WD domain, G-beta repeat
Length: 350 amino acids
Theoretical weight: 38.53 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: P62873 (Residues: 2-340; Coverage: 100%)
Sequence domains: WD domain, G-beta repeat
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
Receptor activity-modifying protein 3
Adrenomedullin-2
Calcitonin gene-related peptide type 1 receptor
