› 6uwm

Electron Microscopy
5.9Å resolution

Single particle cryo-EM structure of KvAP

Released:
DOI: 10.2210/pdb6uwm/pdb
PDB entry 6uwm coloured by chain, front view.
PDB entry 6uwm coloured by chain, side view.
PDB entry 6uwm coloured by chain, top view.
Source organism: Aeropyrum pernix
Primary publication:
Cryo-EM structure of the KvAP channel reveals a non-domain-swapped voltage sensor topology.
Tao X, MacKinnon R
Elife 8 (2019)
PMID: 31755864
Related structures: EMD-20924

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195472 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Voltage-gated potassium channel Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 287 amino acids
Theoretical weight: 31.65 KDa
Source organism: Aeropyrum pernix
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9YDF8 (Residues: 25-295; Coverage: 92%)
Gene name: APE_0955
Sequence domains: Ion transport protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 5.9Å
Relevant EMDB volumes: EMD-20924
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Towards the Idea of Molecular Brains.
Timsit et al. (2021)
1 more

3 mentions without citation

Deep transfer learning for inter-chain contact predictions of transmembrane protein complexes.
Lin et al. (2023)
2 more