6v4f

X-ray diffraction
1.35Å resolution

Crystal Structure Analysis of Zebra Fish MDMX

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-138120 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein Mdm4 Chain: A
Molecule details ›
Chain: A
Length: 104 amino acids
Theoretical weight: 12.13 KDa
Source organism: Danio rerio
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7ZUW7 (Residues: 15-106; Coverage: 19%)
Gene names: mdm4, mdmx
Sequence domains: SWIB/MDM2 domain
Cellular tumor antigen p53 Chain: B
Molecule details ›
Chain: B
Length: 17 amino acids
Theoretical weight: 2.05 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P04637 (Residues: 14-29; Coverage: 4%)
Gene names: P53, TP53
Sequence domains: P53 transactivation motif

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: C2221
Unit cell:
a: 81.14Å b: 108.16Å c: 30.82Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.17 0.169 0.19
Expression systems:
  • Escherichia coli
  • Not provided