› 6v5v

Electron Microscopy
3.8Å resolution

Structure of gamma-tubulin in the native human gamma-tubulin ring complex

Released:
DOI: 10.2210/pdb6v5v/pdb
PDB entry 6v5v coloured by chain, front view.
PDB entry 6v5v coloured by chain, side view.
PDB entry 6v5v coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Asymmetric Molecular Architecture of the Human γ-Tubulin Ring Complex.
Wieczorek M, Urnavicius L, Ti SC, Molloy KR, Chait BT, Kapoor TM
Cell 180 165-175.e16 (2020)
PMID: 31862189
Related structures: EMD-21054

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149909 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tubulin gamma-1 chain Chain: g
Molecule details ›
Chain: g
Length: 451 amino acids
Theoretical weight: 51.26 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P23258 (Residues: 1-451; Coverage: 100%)
Gene names: TUBG, TUBG1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand GDP 1 x GDP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.8Å
Relevant EMDB volumes: EMD-21054

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Citations

16 review citations

Mechanisms of microtubule organization in differentiated animal cells.
Akhmanova et al. (2022)
15 more

3 mentions without citation

Asymmetric Molecular Architecture of the Human γ-Tubulin Ring Complex.
Wieczorek et al. (2020)
2 more