› 6v92

Electron Microscopy
20Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 35-mer (preferred)
PDBe Complex ID:
PDB-CPX-120747 (preferred)
Entry contents:
25 distinct polypeptide molecules
1 distinct DNA molecule
Macromolecules (26 distinct):
Actin-related protein 7 Chain: A
Molecule details ›
Chain: A
Length: 477 amino acids
Theoretical weight: 53.86 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q12406 (Residues: 1-477; Coverage: 100%)
Gene names: ARP7, SWP61, YP9367.14, YPR034W
Sequence domains: Actin
Nuclear protein STH1/NPS1 Chain: R
Molecule details ›
Chain: R
Length: 1359 amino acids
Theoretical weight: 156.98 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P32597 (Residues: 1-1359; Coverage: 100%)
Gene names: NPS1, STH1, YIL126W
Sequence domains:
Actin-like protein ARP9 Chain: B
Molecule details ›
Chain: B
Length: 467 amino acids
Theoretical weight: 53.13 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q05123 (Residues: 1-467; Coverage: 100%)
Gene names: ARP9, SWP59, YM9973.07, YMR033W
Sequence domains: Actin
Regulator of Ty1 transposition protein 102 Chain: P
Molecule details ›
Chain: P
Length: 157 amino acids
Theoretical weight: 17.82 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P53330 (Residues: 1-157; Coverage: 100%)
Gene names: G9378, RTT102, YGR275W
Sequence domains: Rtt102p-like transcription regulator protein
High temperature lethal protein 1 Chain: C
Molecule details ›
Chain: C
Length: 78 amino acids
Theoretical weight: 9.19 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q9URQ5 (Residues: 1-78; Coverage: 100%)
Gene names: DRT1, HTL1, YCR020W-B
Chromatin structure-remodeling complex protein RSC14 Chain: D
Molecule details ›
Chain: D
Length: 180 amino acids
Theoretical weight: 19.83 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P38210 (Residues: 1-180; Coverage: 100%)
Gene names: LDB7, RSC14, YBL006C, YBL0322
Sequence domains: RSC complex, Rsc14/Ldb7 subunit
Chromatin structure-remodeling complex subunit RSC7 Chain: E
Molecule details ›
Chain: E
Length: 435 amino acids
Theoretical weight: 49.72 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P32832 (Residues: 1-435; Coverage: 100%)
Gene names: NPL6, RSC7, YM9582.16C, YMR091C
Sequence domains: Chromatin remodelling complex Rsc7/Swp82 subunit
Chromatin structure-remodeling complex subunit RSC2 Chain: F
Molecule details ›
Chain: F
Length: 889 amino acids
Theoretical weight: 102.44 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q06488 (Residues: 1-889; Coverage: 100%)
Gene names: L9638.1, RSC2, YLR357W
Sequence domains:
Chromatin structure-remodeling complex protein RSC3 Chain: G
Molecule details ›
Chain: G
Length: 885 amino acids
Theoretical weight: 101.83 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q06639 (Residues: 1-885; Coverage: 100%)
Gene names: D9740.13, RSC3, YDR303C
Sequence domains: Fungal Zn(2)-Cys(6) binuclear cluster domain
Chromatin structure-remodeling complex subunit RSC4 Chain: H
Molecule details ›
Chain: H
Length: 625 amino acids
Theoretical weight: 72.37 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q02206 (Residues: 1-625; Coverage: 100%)
Gene names: RSC4, YK107, YKR008W
Sequence domains: Bromodomain
Chromatin structure-remodeling complex protein RSC8 Chains: I, J, K, L
Molecule details ›
Chains: I, J, K, L
Length: 557 amino acids
Theoretical weight: 63.25 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P43609 (Residues: 1-557; Coverage: 100%)
Gene names: RSC8, SWH3, YFR037C
Sequence domains:
Chromatin structure-remodeling complex protein RSC6 Chain: M
Molecule details ›
Chain: M
Length: 483 amino acids
Theoretical weight: 54.22 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P25632 (Residues: 1-483; Coverage: 100%)
Gene names: RSC6, YCR052W, YCR52W
Chromatin structure-remodeling complex subunit RSC9 Chain: N
Molecule details ›
Chain: N
Length: 581 amino acids
Theoretical weight: 65.29 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q03124 (Residues: 1-581; Coverage: 100%)
Gene names: RSC9, YM4987.08, YML127W
Chromatin structure-remodeling complex protein RSC58 Chain: O
Molecule details ›
Chain: O
Length: 502 amino acids
Theoretical weight: 57.87 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q07979 (Residues: 1-502; Coverage: 100%)
Gene names: RSC58, YLR033W
Sequence domains: Bromodomain
Chromatin structure-remodeling complex subunit SFH1 Chain: Q
Molecule details ›
Chain: Q
Length: 426 amino acids
Theoretical weight: 48.83 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q06168 (Residues: 1-426; Coverage: 100%)
Gene names: L8543.4, SFH1, YLR321C
Sequence domains: SNF5 / SMARCB1 / INI1
Chromatin structure-remodeling complex protein RSC30 Chain: S
Molecule details ›
Chain: S
Length: 883 amino acids
Theoretical weight: 101.45 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P38781 (Residues: 1-883; Coverage: 100%)
Gene names: RSC30, YHR056C
Sequence domains: Fungal Zn(2)-Cys(6) binuclear cluster domain
Unknown Protein Chain: 2
Molecule details ›
Chain: 2
Length: 28 amino acids
Theoretical weight: 2.4 KDa
Source organism: Saccharomyces cerevisiae S288C
Unknown Protein Chains: 3, 4
Molecule details ›
Chains: 3, 4
Length: 19 amino acids
Theoretical weight: 1.64 KDa
Source organism: Saccharomyces cerevisiae S288C
Unknown Protein Chain: 5
Molecule details ›
Chain: 5
Length: 14 amino acids
Theoretical weight: 1.21 KDa
Source organism: Saccharomyces cerevisiae S288C
Uuknown Protein Chain: 6
Molecule details ›
Chain: 6
Length: 15 amino acids
Theoretical weight: 1.29 KDa
Source organism: Saccharomyces cerevisiae S288C
Unknown Protein Chain: 7
Molecule details ›
Chain: 7
Length: 49 amino acids
Theoretical weight: 4.19 KDa
Source organism: Saccharomyces cerevisiae S288C
Histone H3.1 Chains: a, e
Molecule details ›
Chains: a, e
Length: 136 amino acids
Theoretical weight: 15.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P68431 (Residues: 1-136; Coverage: 100%)
Gene names: H3C1, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3FA, H3FB, H3FC HIST1H3C, H3FD, H3FF, H3FH, H3FI, H3FJ, H3FK, H3FL, HIST1H3A, HIST1H3B, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J
Sequence domains: Core histone H2A/H2B/H3/H4
Histone H4 Chains: b, f
Molecule details ›
Chains: b, f
Length: 103 amino acids
Theoretical weight: 11.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P62805 (Residues: 1-103; Coverage: 100%)
Gene names: H4-16, H4/A, H4/B, H4/C, H4/D, H4/E, H4/G, H4/H, H4/I, H4/J, H4/K, H4/M, H4/N, H4/O, H4C1, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4F2, H4FA, H4FB, H4FC, H4FD, H4FE, H4FG, H4FH, H4FI, H4FJ, H4FK, H4FM, H4FN, H4FO, HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4, HIST2H4A, HIST2H4B, HIST4H4
Sequence domains: Centromere kinetochore component CENP-T histone fold
Histone H2A type 1-B/E Chains: c, g
Molecule details ›
Chains: c, g
Length: 130 amino acids
Theoretical weight: 14.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P04908 (Residues: 1-130; Coverage: 100%)
Gene names: H2AC4, H2AC8, H2AFA, H2AFM, HIST1H2AB, HIST1H2AE
Sequence domains:
Histone H2B type 1-K Chains: d, h
Molecule details ›
Chains: d, h
Length: 126 amino acids
Theoretical weight: 13.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O60814 (Residues: 1-126; Coverage: 100%)
Gene names: H2BC12, H2BFT, HIRIP1, HIST1H2BK
Sequence domains: Core histone H2A/H2B/H3/H4
DNA (146-MER) Chains: i, j
Molecule details ›
Chains: i, j
Length: 146 nucleotides
Theoretical weight: 45.05 KDa

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 20Å
Relevant EMDB volumes: EMD-21114
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Structure and Function of Chromatin Remodelers.
Reyes et al. (2021)
9 more