› 6vek

X-ray diffraction
2.25Å resolution

Contact-dependent growth inhibition toxin-immunity protein complex from from E. coli 3006, full-length

Released:
DOI: 10.2210/pdb6vek/pdb
PDB entry 6vek coloured by chain, front view.
PDB entry 6vek coloured by chain, side view.
PDB entry 6vek coloured by chain, top view.
Source organism: Escherichia coli 3006
Entry authors: Michalska K, Stols L, Eschenfeldt W, Hayes CS, Goulding CW, Joachimiak A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-104128 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
contact-dependent toxin CdiA Chain: A
Molecule details ›
Chain: A
Length: 338 amino acids
Theoretical weight: 36.61 KDa
Source organism: Escherichia coli 3006
Expression system: Escherichia coli BL21(DE3)
contact-dependent immunity protein CdiI Chain: I
Molecule details ›
Chain: I
Length: 167 amino acids
Theoretical weight: 19.22 KDa
Source organism: Escherichia coli 3006
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A2A2C800 (Residues: 1-161; Coverage: 100%)
Gene names: BTQ06_14240, G3W53_28155

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 41Å b: 71.769Å c: 175.538Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.182 0.234
Expression system: Escherichia coli BL21(DE3)

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