6vnw

Electron Microscopy
3.44Å resolution

Cryo-EM structure of apo-BBSome

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-108020 (preferred)
Entry contents:
8 distinct polypeptide molecules
Macromolecules (8 distinct):
BBSome interacting protein 1 Chain: H
Molecule details ›
Chain: H
Length: 69 amino acids
Theoretical weight: 8.07 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: G3N2W1 (Residues: 1-69; Coverage: 100%)
Gene name: BBIP1
Sequence domains: Cilia BBSome complex subunit 10
Bardet-Biedl syndrome 2 protein homolog Chain: B
Molecule details ›
Chain: B
Length: 721 amino acids
Theoretical weight: 79.91 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: Q32L13 (Residues: 1-721; Coverage: 100%)
Gene name: BBS2
Sequence domains:
Bardet-Biedl syndrome 4 protein homolog Chain: E
Molecule details ›
Chain: E
Length: 519 amino acids
Theoretical weight: 58.29 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: Q1JQ97 (Residues: 1-519; Coverage: 100%)
Gene name: BBS4
Sequence domains:
Bardet-Biedl syndrome 5 protein homolog Chain: G
Molecule details ›
Chain: G
Length: 341 amino acids
Theoretical weight: 38.88 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: A6QLF9 (Residues: 1-341; Coverage: 100%)
Gene name: BBS5
Sequence domains: Bardet-Biedl syndrome 5 protein
Bardet-Biedl syndrome 7 protein homolog Chain: C
Molecule details ›
Chain: C
Length: 715 amino acids
Theoretical weight: 80.47 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: F1MB52 (Residues: 1-715; Coverage: 100%)
Gene name: BBS7
Tetratricopeptide repeat domain 8 Chain: F
Molecule details ›
Chain: F
Length: 501 amino acids
Theoretical weight: 56.69 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: F1N4X0 (Residues: 1-501; Coverage: 100%)
Gene name: TTC8
Sequence domains:
Bardet-Biedl syndrome 9 Chain: I
Molecule details ›
Chain: I
Length: 887 amino acids
Theoretical weight: 99.23 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: E1BHJ5 (Residues: 1-887; Coverage: 100%)
Gene name: BBS9
Sequence domains:
Bardet-Biedl syndrome 1 N-terminal domain-containing protein Chain: D
Molecule details ›
Chain: D
Length: 592 amino acids
Theoretical weight: 64.94 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: E1BN34 (Residues: 76-667; Coverage: 89%)
Gene name: BBS1
Sequence domains: Ciliary BBSome complex subunit 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.44Å
Relevant EMDB volumes: EMD-21251