Function and Biology Details
Reactions catalysed:
4-aminobutanal + NAD(+) + H(2)O = 4-aminobutanoate + NADH
An aldehyde + NAD(+) + H(2)O = a carboxylate + NADH
Formaldehyde + NAD(+) + H(2)O = formate + NADH
4-trimethylammoniobutanal + NAD(+) + H(2)O = 4-trimethylammoniobutanoate + NADH
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
4-trimethylaminobutyraldehyde dehydrogenase (preferred)
PDBe Complex ID:
PDB-CPX-155872 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
4-trimethylaminobutyraldehyde dehydrogenase
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 493 amino acids
Theoretical weight: 53.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Aldehyde dehydrogenase family
Length: 493 amino acids
Theoretical weight: 53.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P49189 (Residues: 2-494; Coverage: 100%)
Sequence domains: Aldehyde dehydrogenase family
