› 6vx3

Electron Microscopy
3.7Å resolution

NaChBac in GDN

Released:
DOI: 10.2210/pdb6vx3/pdb
PDB entry 6vx3 coloured by chain, front view.
PDB entry 6vx3 coloured by chain, side view.
PDB entry 6vx3 coloured by chain, top view.
Source organism: Alkalihalobacillus halodurans C-125
Primary publication:
Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na+ channels in nanodisc.
Gao S, Valinsky WC, On NC, Houlihan PR, Qu Q, Liu L, Pan X, Clapham DE, Yan N
Proc Natl Acad Sci U S A 117 14187-14193 (2020)
PMID: 32513729
Related structures: EMD-21428

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191836 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ion transport domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 274 amino acids
Theoretical weight: 31.49 KDa
Source organism: Alkalihalobacillus halodurans C-125
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9KCR8 (Residues: 1-274; Coverage: 100%)
Gene name: BH1501
Sequence domains: Ion transport protein

Ligands and Environments

1 bound ligand:
Ligand POV 8 x POV
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-21428
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Assessing the Role of Lipids in the Molecular Mechanism of Membrane Proteins.
Jodaitis et al. (2021)
4 more

4 mentions without citation

Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na+ channels in nanodisc.
Gao et al. (2020)
3 more