6w12

X-ray diffraction
2Å resolution

Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to the Tumor-Associated Tn Antigen

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
PDBe Complex ID:
PDB-CPX-184855 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-type lectin domain family 10 member A Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8IUN9 (Residues: 181-308; Coverage: 41%)
Gene names: CLEC10A, CLECSF13, CLECSF14, HML
Sequence domains: Lectin C-type domain

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: P3121
Unit cell:
a: 52.155Å b: 52.155Å c: 112.667Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.169 0.168 0.196
Expression system: Escherichia coli