› 6wb3

X-ray diffraction
1.35Å resolution

Crystal structure of coiled coil region of human septin 4

Released:
DOI: 10.2210/pdb6wb3/pdb
Model geometry
Fit model/data
PDB entry 6wb3 coloured by chain, front view.
PDB entry 6wb3 coloured by chain, side view.
PDB entry 6wb3 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Orientational Ambiguity in Septin Coiled Coils and its Structural Basis.
Leonardo DA, Cavini IA, Sala FA, Mendonça DC, Rosa HVD, Kumagai PS, Crusca E, Valadares NF, Marques IA, Brandão-Neto J, Munte CE, Kalbitzer HR, Soler N, Usón I, André I, Araujo APU, D'Muniz Pereira H, Garratt RC
J Mol Biol 433 166889 (2021)
PMID: 33639214

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128872 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Septin-4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 32 amino acids
Theoretical weight: 3.88 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O43236 (Residues: 448-477; Coverage: 6%)
Gene names: C17orf47, PNUTL2, SEP4, SEPT4, SEPTIN4, hucep-7

Ligands and Environments

2 bound ligands:
Ligand SO4 2 x SO4
Ligand ACT 2 x ACT
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: P212121
Unit cell:
a: 25.763Å b: 41.463Å c: 54.588Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.222 0.247
Expression system: Not provided

Quick links

Citations

2 review citations

Septins From Protists to People.
Shuman et al. (2021)
1 more

2 mentions without citation

The Structural Biology of Septins and Their Filaments: An Update.
Cavini et al. (2021)
1 more