6wiv

Electron Microscopy
3.3Å resolution

Structure of human GABA(B) receptor in an inactive state

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-131164 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Gamma-aminobutyric acid type B receptor subunit 1 Chain: A
Molecule details ›
Chain: A
Length: 810 amino acids
Theoretical weight: 91.59 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9UBS5 (Residues: 153-919; Coverage: 81%)
Gene names: GABBR1, GPRC3A
Sequence domains:
Gamma-aminobutyric acid type B receptor subunit 2 Chain: B
Molecule details ›
Chain: B
Length: 827 amino acids
Theoretical weight: 93.28 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O75899 (Residues: 1-819; Coverage: 86%)
Gene names: GABBR2, GPR51, GPRC3B
Sequence domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.3Å
Relevant EMDB volumes: EMD-21685
Expression system: Homo sapiens