Function and Biology Details
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- RNA polymerase sigma-70
- Glutathione S-transferase, N-terminal
- DNA-directed RNA polymerase, RpoA/D/Rpb3-type
- RNA polymerase, RBP11-like subunit
- DNA-directed RNA polymerase, alpha subunit
- DNA-directed RNA polymerase, omega subunit
- DNA-directed RNA polymerase, insert domain superfamily
- Winged helix-like DNA-binding domain superfamily
48 more domains
Structure analysis Details
Assembly composition:
hetero tetradecamer (preferred)
PDBe Complex ID:
PDB-CPX-100904 (preferred)
Entry contents:
9 distinct polypeptide molecules
4 distinct DNA molecules
4 distinct DNA molecules
Macromolecules (13 distinct):
DNA-directed RNA polymerase subunit omega
Molecule details ›
Chain: E
Length: 72 amino acids
Theoretical weight: 8.18 KDa
Source organism: Francisella tularensis subsp. holarctica LVS
UniProt:
Sequence domains: RNA polymerase Rpb6
Length: 72 amino acids
Theoretical weight: 8.18 KDa
Source organism: Francisella tularensis subsp. holarctica LVS
UniProt:
- Canonical:
Q2A273 (Residues: 1-72; Coverage: 100%)
Sequence domains: RNA polymerase Rpb6
DNA-directed RNA polymerase subunit alpha 1
Molecule details ›
Chain: A
Length: 323 amino acids
Theoretical weight: 35.39 KDa
Source organism: Francisella tularensis subsp. holarctica LVS
UniProt:
Sequence domains:
Length: 323 amino acids
Theoretical weight: 35.39 KDa
Source organism: Francisella tularensis subsp. holarctica LVS
UniProt:
- Canonical: Q2A5E5 (Residues: 1-323; Coverage: 100%)
Sequence domains:
DNA-directed RNA polymerase subunit alpha 2
Molecule details ›
Chain: B
Length: 317 amino acids
Theoretical weight: 35.11 KDa
Source organism: Francisella tularensis subsp. holarctica LVS
UniProt:
Sequence domains:
Length: 317 amino acids
Theoretical weight: 35.11 KDa
Source organism: Francisella tularensis subsp. holarctica LVS
UniProt:
- Canonical: Q2A4H7 (Residues: 1-317; Coverage: 100%)
Sequence domains:
DNA-directed RNA polymerase subunit beta
Molecule details ›
Chain: C
Length: 1358 amino acids
Theoretical weight: 151.54 KDa
Source organism: Francisella tularensis subsp. holarctica LVS
UniProt:
Sequence domains:
Length: 1358 amino acids
Theoretical weight: 151.54 KDa
Source organism: Francisella tularensis subsp. holarctica LVS
UniProt:
- Canonical: Q2A1M7 (Residues: 1-1358; Coverage: 100%)
Sequence domains:
DNA-directed RNA polymerase subunit beta'
Molecule details ›
Chain: D
Length: 1604 amino acids
Theoretical weight: 178.45 KDa
Source organism: Francisella tularensis subsp. holarctica LVS
UniProt:
Sequence domains:
Length: 1604 amino acids
Theoretical weight: 178.45 KDa
Source organism: Francisella tularensis subsp. holarctica LVS
UniProt:
- Canonical: Q2A1M8 (Residues: 1-1417; Coverage: 100%)
Sequence domains:
GST N-terminal domain-containing protein
Molecule details ›
Chain: M
Length: 205 amino acids
Theoretical weight: 23.65 KDa
Source organism: Francisella tularensis subsp. holarctica LVS
UniProt:
Sequence domains: Glutathione S-transferase, N-terminal domain
Length: 205 amino acids
Theoretical weight: 23.65 KDa
Source organism: Francisella tularensis subsp. holarctica LVS
UniProt:
- Canonical: A0A0B6CT24 (Residues: 1-205; Coverage: 100%)
Sequence domains: Glutathione S-transferase, N-terminal domain
RNA polymerase sigma factor RpoD
Molecule details ›
Chain: Z
Length: 577 amino acids
Theoretical weight: 67.75 KDa
Source organism: Francisella tularensis subsp. holarctica LVS
UniProt:
Sequence domains:
Length: 577 amino acids
Theoretical weight: 67.75 KDa
Source organism: Francisella tularensis subsp. holarctica LVS
UniProt:
- Canonical: A0A0B3WH85 (Residues: 1-577; Coverage: 100%)
Sequence domains:
