› 6wu2

Electron Microscopy
3.36Å resolution

Structure of the LaINDY-malate complex

Released:
DOI: 10.2210/pdb6wu2/pdb
PDB entry 6wu2 coloured by chain, front view.
PDB entry 6wu2 coloured by chain, side view.
PDB entry 6wu2 coloured by chain, top view.
Source organism: Lactobacillus acidophilus
Primary publication:
Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Sauer DB, Trebesch N, Marden JJ, Cocco N, Song J, Koide A, Koide S, Tajkhorshid E, Wang DN
Elife 9 (2020)
PMID: 32869741
Related structures: EMD-21903

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177108 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2-oxoglutarate-malate translocator Chains: A, B
Molecule details ›
Chains: A, B
Length: 516 amino acids
Theoretical weight: 56.56 KDa
Source organism: Lactobacillus acidophilus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5FKK5 (Residues: 1-488; Coverage: 100%)
Gene name: LBA0912
Sequence domains: Sodium:sulfate symporter transmembrane region

Ligands and Environments

3 bound ligands:
Ligand HEX 6 x HEX
Ligand D10 2 x D10
Ligand OCT 2 x OCT
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.36Å
Relevant EMDB volumes: EMD-21903
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Membranes under the Magnetic Lens: A Dive into the Diverse World of Membrane Protein Structures Using Cryo-EM.
Piper et al. (2022)
1 more

1 mention without citation

Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Sauer et al. (2020)