› 6wzo

X-ray diffraction
1.42Å resolution

Structure of SARS-CoV-2 Nucleocapsid dimerization domain, P1 form

Released:
DOI: 10.2210/pdb6wzo/pdb
PDB entry 6wzo coloured by chain, front view.
PDB entry 6wzo coloured by chain, side view.
PDB entry 6wzo coloured by chain, top view.
Source organism: Severe acute respiratory syndrome coronavirus 2
Primary publication:
Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein.
Ye Q, West AMV, Silletti S, Corbett KD
Protein Sci 29 1890-1901 (2020)
PMID: 32654247

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145015 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoprotein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 121 amino acids
Theoretical weight: 13.53 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DTC9 (Residues: 247-364; Coverage: 28%)
Gene name: N
Sequence domains: Coronavirus nucleocapsid

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P1
Unit cell:
a: 43.718Å b: 50.061Å c: 69.337Å
α: 106.499° β: 90.094° γ: 97.145°
R-values:
R R work R free
0.158 0.157 0.173
Expression system: Escherichia coli

Quick links

Citations

31 review citations

Structural Characterization of SARS-CoV-2: Where We Are, and Where We Need to Be.
Mariano et al. (2020)
30 more

32 mentions without citation

Structural insights into SARS-CoV-2 proteins.
Arya et al. (2021)
31 more