Function and Biology Details
Reaction catalysed:
NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-120892 (preferred)
Entry contents:
2 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (4 distinct):
Histone PARylation factor 1
Molecule details ›
Chain: O
Length: 356 amino acids
Theoretical weight: 40.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Histone PARylation factor 1
Length: 356 amino acids
Theoretical weight: 40.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9NWY4 (Residues: 1-346; Coverage: 100%)
Sequence domains: Histone PARylation factor 1
Poly [ADP-ribose] polymerase 2
Molecule details ›
Chains: P, R
Length: 590 amino acids
Theoretical weight: 67.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 590 amino acids
Theoretical weight: 67.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9UGN5 (Residues: 1-583; Coverage: 98%)
Sequence domains:
