Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Neurotransmitter-gated ion-channel
- Gamma-aminobutyric acid A receptor/Glycine receptor alpha
- Immunoglobulin C1-set
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like fold
- Immunoglobulin-like domain
- Gamma-aminobutyric-acid A receptor, alpha subunit
- Neurotransmitter-gated ion-channel ligand-binding domain superfamily
12 more domains
Structure analysis Details
Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-210616 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (8 distinct):
Gamma-aminobutyric acid receptor subunit beta-2
Molecule details ›
Chains: A, C
Length: 364 amino acids
Theoretical weight: 41.81 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 364 amino acids
Theoretical weight: 41.81 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P47870 (Residues: 25-331, 487-512; Coverage: 68%)
Sequence domains:
Gamma-aminobutyric acid receptor subunit alpha-1
Molecule details ›
Chains: B, D
Length: 358 amino acids
Theoretical weight: 41.06 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 358 amino acids
Theoretical weight: 41.06 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P14867 (Residues: 28-339, 419-456; Coverage: 82%)
Sequence domains:
Gamma-aminobutyric acid receptor subunit gamma-2
Molecule details ›
Chain: E
Length: 417 amino acids
Theoretical weight: 47.67 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 417 amino acids
Theoretical weight: 47.67 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P18507 (Residues: 8-361, 448-475; Coverage: 78%)
Sequence domains:
