Function and Biology Details
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- P-loop containing nucleoside triphosphate hydrolase
- DNA-directed RNA polymerase, insert domain superfamily
- DNA-directed RNA polymerase, RpoA/D/Rpb3-type
- RNA polymerase, RBP11-like subunit
- DNA-directed RNA polymerase, alpha subunit
- DNA-directed RNA polymerase, omega subunit
- Helicase, C-terminal domain-like
- RNA polymerase, subunit omega/Rpo6/RPB6
36 more domains
Structure analysis Details
Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-120899 (preferred)
Entry contents:
5 distinct polypeptide molecules
2 distinct DNA molecules
1 distinct RNA molecule
2 distinct DNA molecules
1 distinct RNA molecule
Macromolecules (8 distinct):
Transcription-repair-coupling factor
Molecule details ›
Chain: A
Length: 1148 amino acids
Theoretical weight: 130.15 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 1148 amino acids
Theoretical weight: 130.15 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P30958 (Residues: 1-1148; Coverage: 100%)
Sequence domains:
DNA-directed RNA polymerase subunit alpha
Molecule details ›
DNA-directed RNA polymerase subunit beta
DNA-directed RNA polymerase subunit beta'
DNA-directed RNA polymerase subunit omega
