6x97

Electron Microscopy
3.65Å resolution

Cryo-EM model of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 11A fragment antigen binding variable domain

Released:
Entry authors: Ozorowski G, Cottrell CA, Ward AB
Related structures: EMD-22103

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-212169 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (6 distinct):
Transmembrane protein gp41 Chains: A, C, G
Molecule details ›
Chains: A, C, G
Length: 516 amino acids
Theoretical weight: 57.95 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 30-510; Coverage: 56%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120
Transmembrane protein gp41 Chains: B, D, I
Molecule details ›
Chains: B, D, I
Length: 153 amino acids
Theoretical weight: 17.15 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 509-661; Coverage: 18%)
Gene name: env
Sequence domains: Retroviral envelope protein
monoclonal antibody 11A fragment antigen binding heavy chain Chains: E, H, J
monoclonal antibody 11A kappa chain Chains: F, K, L

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA
1 bound ligand:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.65Å
Relevant EMDB volumes: EMD-22103
Expression system: Homo sapiens