› 6xcm

Electron Microscopy
3.42Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-210127 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (7 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1259 amino acids
Theoretical weight: 139.79 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1213; Coverage: 95%)
Gene names: 2, S
Sequence domains:
C105 Fab Heavy Chain Chains: H, N
Molecule details ›
Chains: H, N
Length: 230 amino acids
Theoretical weight: 24.66 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
C105 Fab Light Chain Chains: L, S
Molecule details ›
Chains: L, S
Length: 217 amino acids
Theoretical weight: 22.89 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
1 bound ligand:
Ligand NAG 30 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.42Å
Relevant EMDB volumes: EMD-22127
Expression system: Homo sapiens

Quick links

Citations

79 review citations

Structural Characterization of SARS-CoV-2: Where We Are, and Where We Need to Be.
Mariano et al. (2020)
78 more

41 mentions without citation

The SARS-CoV-2 Spike Glycoprotein as a Drug and Vaccine Target: Structural Insights into Its Complexes with ACE2 and Antibodies.
Papageorgiou et al. (2020)
40 more