› 6xcn

Electron Microscopy
3.66Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-210128 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (6 distinct):
Spike glycoprotein Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 1259 amino acids
Theoretical weight: 139.79 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1213; Coverage: 95%)
Gene names: 2, S
Sequence domains:
C105 Fab Heavy Chain Chains: B, F, H
Molecule details ›
Chains: B, F, H
Length: 230 amino acids
Theoretical weight: 24.66 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
C105 Fab Light Chain Chains: D, G, L
Molecule details ›
Chains: D, G, L
Length: 217 amino acids
Theoretical weight: 22.89 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
1 bound ligand:
Ligand NAG 24 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.66Å
Relevant EMDB volumes: EMD-22128
Expression system: Homo sapiens

Quick links

Citations

80 review citations

Structural Characterization of SARS-CoV-2: Where We Are, and Where We Need to Be.
Mariano et al. (2020)
79 more

43 mentions without citation

The SARS-CoV-2 Spike Glycoprotein as a Drug and Vaccine Target: Structural Insights into Its Complexes with ACE2 and Antibodies.
Papageorgiou et al. (2020)
42 more