› 6xjh

Electron Microscopy
3.6Å resolution

PmtCD ABC exporter without the basket domain at C2 symmetry

Released:
DOI: 10.2210/pdb6xjh/pdb
PDB entry 6xjh coloured by chain, front view.
PDB entry 6xjh coloured by chain, side view.
PDB entry 6xjh coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins.
Zeytuni N, Dickey SW, Hu J, Chou HT, Worrall LJ, Alexander JAN, Carlson ML, Nosella M, Duong F, Yu Z, Otto M, Strynadka NCJ
Sci Adv 6 (2020)
PMID: 32998902
Related structures: EMD-22210

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173437 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Phenol-soluble modulin export ABC transporter permease subunit PmtD Chains: A, B
Molecule details ›
Chains: A, B
Length: 266 amino acids
Theoretical weight: 30.49 KDa
Source organism: Staphylococcus aureus
Expression system: Staphylococcus aureus
UniProt:
  • Canonical: Q2FWX0 (Residues: 2-246; Coverage: 100%)
Gene name: SAOUHSC_02151
Sequence domains: ABC-2 family transporter protein
ABC transporter domain-containing protein Chains: C, D
Molecule details ›
Chains: C, D
Length: 290 amino acids
Theoretical weight: 33 KDa
Source organism: Staphylococcus aureus
Expression system: Staphylococcus aureus
UniProt:
  • Canonical: X5EJW5 (Residues: 1-290; Coverage: 100%)
Gene names: A6760_10570, BN1321_320024, E1948_10220, E1948_12950, EP54_10395, EQ90_13985, FAF17_08450, G6W63_11405, GO793_05685, GO814_14410, GO942_00400, GQX37_09960, GZ156_13550, GZ163_10835, HMPREF3211_02244, NCTC13131_01274, NCTC7878_02640, NCTC7972_03024, QU38_06870, SAMEA1531744_02479, SAMEA2078260_02035, SAMEA2078588_01769, SAMEA2080344_01931, SAMEA2081063_01946, SAMEA4008575_02323, SAMEA70146418_02072, SAMEA70245418_02239, pmtC, ybhF_1, ybhF_2, ybhF_3
Sequence domains: ABC transporter

Ligands and Environments

2 bound ligands:
Ligand AGS 2 x AGS
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.6Å
Relevant EMDB volumes: EMD-22210
Expression system: Staphylococcus aureus

Quick links

Citations

3 review citations

The microbiome-shaping roles of bacteriocins.
Heilbronner et al. (2021)
2 more

2 mentions without citation

Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins.
Zeytuni et al. (2020)
1 more