› 6xk2

X-ray diffraction
2.5Å resolution

Crystal structure of Ribokinase from Cryptococcus neoformans var. grubii serotype A in complex with ADP

Released:
DOI: 10.2210/pdb6xk2/pdb
PDB entry 6xk2 coloured by chain, front view.
PDB entry 6xk2 coloured by chain, side view.
PDB entry 6xk2 coloured by chain, top view.
Source organism: Cryptococcus neoformans var. grubii H99
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed: 
ATP + D-ribose = ADP + D-ribose 5-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125427 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribokinase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 332 amino acids
Theoretical weight: 35.09 KDa
Source organism: Cryptococcus neoformans var. grubii H99
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: J9VQ51 (Residues: 1-324; Coverage: 100%)
Gene name: CNAG_02296
Sequence domains: pfkB family carbohydrate kinase

Ligands and Environments

3 bound ligands:
Ligand ADP 4 x ADP
Ligand EDO 3 x EDO
Ligand NA 3 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P21
Unit cell:
a: 77.17Å b: 84.57Å c: 98.27Å
α: 90° β: 95.27° γ: 90°
R-values:
R R work R free
0.183 0.181 0.23
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'

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